null

SMILES Cn1cc(CCNCc2ccc(\C=C\C(=O)NO)cc2)c2ccccc12

InChI Key InChIKey=AEDUBEGTPWKDCX-ZHACJKMWSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 323704   

TargetHistone deacetylase 1(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z75CXUS Patent
TargetHistone deacetylase 9(Homo sapiens (Human))TBA
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 4.85E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 3(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z75CXUS Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 655nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z75CXUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z75CXUS Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z75CXUS Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 2.04E+3nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z75CXUS Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+3nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z75CXUS Patent
TargetHistone deacetylase 9(Homo sapiens (Human))TBA
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 4.85E+3nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z75CXUS Patent
TargetHistone deacetylase(Homo sapiens (Human))
Novartis Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against histone deacetylase (HDAC) enzyme obtained from H1299 human lung carcinoma cell lysatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TP0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 3(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 4(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 655nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 5(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 99nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 6(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 7(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 2.04E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 8(Homo sapiens (Human))
The General Hospital Corporation

US Patent
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM323704(US10188756, Compound CN107)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:All histone deacetylases were purchased from BPS Bioscience. The substrates, Broad Substrate A, and Broad Substrate B, were synthesized and are now a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z75CXUS Patent