null

SMILES CSc1nc(nn1C(=O)c1ccc(C)cc1)-c1ccco1

InChI Key InChIKey=QOLOIIDNXILJRE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 32796   

TargetProthrombin(Homo sapiens (Human))
PCMD

Curated by PubChem BioAssay
LigandPNGBDBM32796(MLS000115326 | SMR000092470 | [3-(2-furanyl)-5-(me...)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64GDNPCBioAssay
TargetCoagulation factor XI(Homo sapiens (Human))
PCMD

Curated by PubChem BioAssay
LigandPNGBDBM32796(MLS000115326 | SMR000092470 | [3-(2-furanyl)-5-(me...)copy SMILEScopy InChI
Affinity DataIC50: 531nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993J6PCBioAssay
TargetComplement C1s subcomponent(Homo sapiens (Human))
PCMD

Curated by PubChem BioAssay
LigandPNGBDBM32796(MLS000115326 | SMR000092470 | [3-(2-furanyl)-5-(me...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Dr. Scott L. Diamond, University of Pen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP51PCPCBioAssay
TargetKallikrein-5(Homo sapiens (Human))
PCMD

Curated by PubChem BioAssay
LigandPNGBDBM32796(MLS000115326 | SMR000092470 | [3-(2-furanyl)-5-(me...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9GC8PCBioAssay
TargetCathepsin G(Homo sapiens (Human))
PCMD

Curated by PubChem BioAssay
LigandPNGBDBM32796(MLS000115326 | SMR000092470 | [3-(2-furanyl)-5-(me...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8R8BPCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
PCMD

Curated by PubChem BioAssay
LigandPNGBDBM32796(MLS000115326 | SMR000092470 | [3-(2-furanyl)-5-(me...)copy SMILEScopy InChI
Affinity DataIC50: 2.46E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0JQSPCBioAssay
TargetComplement C1s subcomponent(Homo sapiens (Human))
PCMD

Curated by PubChem BioAssay
LigandPNGBDBM32796(MLS000115326 | SMR000092470 | [3-(2-furanyl)-5-(me...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsyl...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20000GWPCBioAssay