null

SMILES COc1ccc(CC2CCN(CC2)C(=O)c2ccc(nc2)C(=O)NC2CCN(Cc3ccc(cc3)C#N)CC2)cc1

InChI Key InChIKey=CXYVYGXMFQSTKH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 327994   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM327994(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)copy SMILEScopy InChI
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26975P8US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM327994(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM327994(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1HM7PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM327994(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(4-(4- met...)copy SMILEScopy InChI
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0R22US Patent