null

SMILES Oc1c2C(=O)N3[C@H]4CC[C@H](C4)O[C@@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O

InChI Key InChIKey=SOLUWJRYJLAZCX-LYOVBCGYSA-N

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 330048   

TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM330048((2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluor...)copy SMILEScopy InChI
Affinity DataKi:  3.02E+5nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1069FPubMed
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330048((2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 487nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetIntegrase(Human immunodeficiency virus 1)TBA
LigandPNGBDBM330048((2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluor...)copy SMILEScopy InChI
Affinity DataEC50:  3.10nMMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 2(Homo sapiens (Human))TBA
LigandPNGBDBM330048((2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 487nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF310SUS Patent
TargetSolute carrier family 22 member 2(Homo sapiens (Human))TBA
LigandPNGBDBM330048((2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 487nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24F1SVFUS Patent
TargetIntegrase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM330048((2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of HIV integrase strand transfer activityMore data for this Ligand-Target Pair