null

SMILES CC1=CC(=O)c2c(O)ccc(O)c2C1=O

InChI Key InChIKey=YKPXIWHBRBFRQM-UHFFFAOYSA-N

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 33201   

TargetBcl-2-related protein A1(Homo sapiens (Human))
NMMLSC

Curated by PubChem BioAssay
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)copy SMILEScopy InChI
Affinity DataEC50:  2.87E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN728NPCBioAssay
TargetGlutathione S-transferase Mu 1(Homo sapiens (Human))
NMMLSC

Curated by PubChem BioAssay
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)copy SMILEScopy InChI
Affinity DataEC50:  2.14E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61HPTPCBioAssay
TargetEukaryotic translation initiation factor 4 gamma 1(Homo sapiens (Human))
Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3686PCBioAssay
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of TrxR1 in human HL60 cells incubated for 24 hrs by endpoint insulin reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5WWXPubMed
TargetProtein Rev(Human immunodeficiency virus 1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)copy SMILEScopy InChI
Affinity DataIC50: 7.54E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0CZGPCBioAssay
TargetFemale germline-specific tumor suppressor gld-1(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)copy SMILEScopy InChI
Affinity DataIC50: 5.58E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC01ZWPCBioAssay
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of NADPH-reduced rat TrxR1 assessed as suppression of DTNB reduction incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5WWXPubMed
TargetCore protein(Hepatitis C virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33201(2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.98E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z939RPCBioAssay