null
SMILES CC(C)c1ccc(O)c(=O)c(O)c1
InChI Key InChIKey=HVGNSPLLPQWYGC-UHFFFAOYSA-N
PDB links: 4 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 33411
Affinity DataIC50: 660nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMpH: 7.8 T: 2°CAssay Description:To compare activity and inhibition of E. coli RNase H with HIV-1 RNase H, theconcentration of the E. coli was adjusted to the efficiency of 500 nM HI...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Food and Drug Administration
Curated by ChEMBL
Food and Drug Administration
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human immunodeficiency virus-1 reverse transcriptase associated RNase H activity using using 18-nucleotide 3,-fluorescein-labeled RNA s...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 2)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of RNase H activity of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Food and Drug Administration
Curated by ChEMBL
Food and Drug Administration
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase H activity expressed in Escherichia coli using 32P-labeled template 31Trna RNA and DNA oligonucleotide...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HIV-1 BH10 reverse transcriptase RNase H activity expressed in Escherichia coli using [32P]-labeled template primer 31Trna/21P as subst...More data for this Ligand-Target Pair