null

SMILES On1c(=O)[nH]c2ccccc2c1=O

InChI Key InChIKey=TZZSQUATPYDROZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 33412   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataKi:  104nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5QG3PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataKi:  480nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5QG3PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5QG3PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5QG3PubMed
TargetFlap endonuclease 1(Homo sapiens (Human))TBA
LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataIC50: 241nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MS3WZKUS Patent
TargetFlap endonuclease 1(Homo sapiens (Human))TBA
LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of FEN1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4RQ2PubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys, Inc.

Curated by ChEMBL
LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibitory concentration against the xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7V46PubMed
TargetFlap endonuclease 1(Homo sapiens (Human))TBA
LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataIC50: 0.0790nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7V46PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetDeoxyribonuclease-1(Homo sapiens (Human))
MRC Technology

Curated by ChEMBL
LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DNAse1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4RQ2PubMed