null

SMILES COc1ccc(cc1OC)C(=O)n1nc(nc1N)-c1ccccc1

InChI Key InChIKey=KJFHJZMOFADPOP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 33437   

TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61JVPubMed
TargetKallikrein-14(Homo sapiens (Human))
Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMpH: 8.0Assay Description:Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61JVPubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61JVPubMed
TargetKallikrein-7(Homo sapiens (Human))
Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61JVPubMed
TargetKallikrein-5(Homo sapiens (Human))
PCMD

Curated by PubChem BioAssay
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 2.12E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9GC8PCBioAssay
TargetCathepsin G(Homo sapiens (Human))
PCMD

Curated by PubChem BioAssay
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 4.43E+3nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8R8BPCBioAssay
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BC8PCBioAssay
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 1.92E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK996KPCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
PCMD

Curated by PubChem BioAssay
LigandPNGBDBM33437((5-amino-3-phenyl-1,2,4-triazol-1-yl)-(3,4-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMpH: 7.4 T: 2°CAssay Description:HTS was performed on a total of 33,068 compounds of the MLSCN library, 23,017 of which were not in the mixture HTS plates used previously. These comp...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6HQBPCBioAssay