null

SMILES CCCCN(Cc1ccc(cc1)C(=O)NO)C(=O)Nc1ncccn1

InChI Key InChIKey=NGUQTALSXMYZCZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 337664   

TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM337664(US10227295, Compound JB6-22 | US9751832, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 2.74E+3nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23T9KBRUS Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM337664(US10227295, Compound JB6-22 | US9751832, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 9.76nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23T9KBRUS Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM337664(US10227295, Compound JB6-22 | US9751832, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 2.74E+3nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280B3GPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM337664(US10227295, Compound JB6-22 | US9751832, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 9.76nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD71RFUS Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM337664(US10227295, Compound JB6-22 | US9751832, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human full length HDAC6 expressed in baculovirus infected Sf9 insect cells using p53 (379 to 382 residues) derived RHKKAc a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280B3GPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM337664(US10227295, Compound JB6-22 | US9751832, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 2.74E+3nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD71RFUS Patent