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SMILES Cn1ccc2cc(ccc12)-c1nc(n2ccnc(N)c12)C(C)(C)C

InChI Key InChIKey=CSXUIGRDFNAIAL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 340945   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through its Center for Commercialization

US Patent
LigandPNGBDBM340945(3-tert-butyl-1-(1-methyl-1H-indol-5- yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MVCUS Patent
TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
University of Washington Through its Center for Commercialization

US Patent
LigandPNGBDBM340945(3-tert-butyl-1-(1-methyl-1H-indol-5- yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Two types of enzyme assays were developed to follow TgCDPK1 activity, a radiometric scintillation proximity assay measured the labeled γ-phospha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MVCUS Patent
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through its Center for Commercialization

US Patent
LigandPNGBDBM340945(3-tert-butyl-1-(1-methyl-1H-indol-5- yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D79DSFUS Patent
LigandPNGBDBM340945(3-tert-butyl-1-(1-methyl-1H-indol-5- yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K077GQUS Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO

US Patent
LigandPNGBDBM340945(3-tert-butyl-1-(1-methyl-1H-indol-5- yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D79DSFUS Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO

US Patent
LigandPNGBDBM340945(3-tert-butyl-1-(1-methyl-1H-indol-5- yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 4.79E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D79DSFUS Patent
LigandPNGBDBM340945(3-tert-butyl-1-(1-methyl-1H-indol-5- yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K077GQUS Patent
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO

US Patent
LigandPNGBDBM340945(3-tert-butyl-1-(1-methyl-1H-indol-5- yl)imidazo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D79DSFUS Patent