null

SMILES CCN(CC)CCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=ULIJLYCJYRQKBG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 3431   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pfizer

LigandPNGBDBM3431(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 660nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48DGPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM3431(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 82nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48DGPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3431(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31XRRPubMed
TargetInsulin receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3431(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31XRRPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3431(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31XRRPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3431(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 73nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48DGPubMed