null

SMILES CN1CCN(CCCNc2ncc3cc(c(NC(N)=O)nc3n2)-c2c(Cl)cccc2Cl)CC1

InChI Key InChIKey=TWSKIHWXLLKVLC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3468   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pfizer

LigandPNGBDBM3468(6-arylpyrido[2,3-d]pyrimidine deriv. 50 | [6-(2,6-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48DGPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM3468(6-arylpyrido[2,3-d]pyrimidine deriv. 50 | [6-(2,6-...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48DGPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM3468(6-arylpyrido[2,3-d]pyrimidine deriv. 50 | [6-(2,6-...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48DGPubMed