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SMILES O=C(Nc1ccccc1)Nc1cccc(c1)[C@H]1CCCN(C1)c1ncnc2[nH]ccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 348542   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.; Biogen MA Inc.

US Patent
LigandPNGBDBM348542(US10577374, Compound 265 | US9790229, Compound 265)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22809RKUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.; Biogen MA Inc.

US Patent
LigandPNGBDBM348542(US10577374, Compound 265 | US9790229, Compound 265)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Reversible inhibition of recombinant full-length N-terminal 6-His-tagged human BTK expressed in baculovirus infected Sf21 insect cells using fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3JSFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.; Biogen MA Inc.

US Patent
LigandPNGBDBM348542(US10577374, Compound 265 | US9790229, Compound 265)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:BTK-POLYGAT-LS ASSAY. The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2805502US Patent