null

SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCC[C@@H](C)C(=O)Nc2c1)NC(=O)c1cnn(c1C)-c1cccc(Cl)c1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350469   

TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM350469(US10208068, Example 40)copy SMILES
Affinity DataKi:  2.10nMAssay Description:Inhibition of human activated factor XI using pyro-Glu-Pro-Arg-pNA as substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67M9SPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM350469(US10208068, Example 40)copy SMILES
Affinity DataKi: <5nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89FHKUS Patent