null

SMILES CCn1c2nc(Sc3nc4ccccc4[nH]3)n(Cc3ccccc3)c2c(=O)[nH]c1=O

InChI Key InChIKey=JSUKDSWMYLASNP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 357743   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

US Patent
LigandPNGBDBM357743(MW-01-139/(I-46) | US10214530, Example 52)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04SKUS Patent
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM357743(MW-01-139/(I-46) | US10214530, Example 52)copy SMILEScopy InChI
Affinity DataIC50: 47nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164VFPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

US Patent
LigandPNGBDBM357743(MW-01-139/(I-46) | US10214530, Example 52)copy SMILEScopy InChI
Affinity DataIC50: 820nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164VFPubMed
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM357743(MW-01-139/(I-46) | US10214530, Example 52)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04SKUS Patent