null

SMILES O=c1[nH]c(=O)c2n(Cc3ccccc3)c(Cc3nc4ccccc4[nH]3)nc2n1C1CC1

InChI Key InChIKey=GLUWCNQLKSIYKQ-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 357744   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

US Patent
LigandPNGBDBM357744(KM-05-80/(I-1) | US10214530, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM357744(KM-05-80/(I-1) | US10214530, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164VFPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

US Patent
LigandPNGBDBM357744(KM-05-80/(I-1) | US10214530, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 850nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM357744(KM-05-80/(I-1) | US10214530, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04SKUS Patent