null

SMILES Cn1c2nc(Sc3nc4cc(NC(=O)CC[C@H](N)C(O)=O)ccc4[nH]3)n(Cc3ccccc3)c2c(=O)[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 357756   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

US Patent
LigandPNGBDBM357756(KM480/(I-41) | US10214530, Example 47)copy SMILES
Affinity DataIC50: 2.95E+3nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04SKUS Patent
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM357756(KM480/(I-41) | US10214530, Example 47)copy SMILES
Affinity DataIC50: 230nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164VFPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

US Patent
LigandPNGBDBM357756(KM480/(I-41) | US10214530, Example 47)copy SMILES
Affinity DataIC50: 2.95E+3nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164VFPubMed
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM357756(KM480/(I-41) | US10214530, Example 47)copy SMILES
Affinity DataIC50: 230nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04SKUS Patent