null

SMILES COc1ccc2[nH]c(Sc3nc4n(C)c(=O)[nH]c(=O)c4n3Cc3ccccc3)nc2c1

InChI Key InChIKey=LGBAGECDKRRUFJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357765   

TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

US Patent
LigandPNGBDBM357765(KM422/(I-25) | US10214530, Example 31)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04SKUS Patent
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

US Patent
LigandPNGBDBM357765(KM422/(I-25) | US10214530, Example 31)copy SMILEScopy InChI
Affinity DataIC50: 9.48E+3nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04SKUS Patent