null

SMILES Nc1nc2oc3ccc(cc3c(=O)c2cc1C(O)=O)C1=CCC2(CC1)OCCO2

InChI Key InChIKey=OSKHCVGUWCGWIV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 357895   

TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN

US Patent
LigandPNGBDBM357895(US10214536, Compound 78)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Kinase assays are commonly used for determining the ability of a small molecule to inhibit enzyme activity. By measuring the degree of phosphorylatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N87D2SUS Patent
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM357895(US10214536, Compound 78)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human IKKepsilon (1 to 655 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M04858PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN

US Patent
LigandPNGBDBM357895(US10214536, Compound 78)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of human TBK1 (1 to 657 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M04858PubMed