null

SMILES OC(CN1CCN(CCS(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)Cc1ccccc1

InChI Key InChIKey=MACFTPBZAOCTFN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 364423   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  2.53nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  2.53nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7TRGUS Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  2.53nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  176nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  176nMMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

US Patent
LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  336nMMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

US Patent
LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  336nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  4.61E+3nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  4.61E+3nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7TRGUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  4.61E+3nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetTransporter(Rattus norvegicus (rat))TBA
LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7TRGUS Patent
TargetTransporter(Rattus norvegicus (rat))TBA
LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, frontal cortex dissected and rapidly frozen. M...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetNeuroepithelial cell-transforming 1(Rat)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

US Patent
LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent