null
SMILES CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)[C@H](NC(=O)c2cccc(C)c2)C2CCOCC2)C1=O
InChI Key InChIKey=LEQNBKIUGXBMTP-RUZDIDTESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 369899
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
X-Chem, Inc.
Curated by ChEMBL
X-Chem, Inc.
Curated by ChEMBL
Affinity DataIC50: 623nMAssay Description:Inhibition of C-terminal FLAG-tagged human autotaxin expressed in Freestyle 293 cells assessed as reduction in choline release from LPC 16:0 pre-incu...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
X-Chem, Inc.
Curated by ChEMBL
X-Chem, Inc.
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair