null

SMILES CC(C)[C@@H](NC(=O)c1cc(ccc1F)C(F)(F)F)C(=O)N1CCC2(CC1)N(C(=O)N(C)C2=O)c1ccccc1

InChI Key InChIKey=TXPSXZIHPCEXFF-OAQYLSRUSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 369934   

LigandPNGBDBM369934((R)-2-Fluoro-N-(3-methyl-1-(3-methyl-2,4-dioxo-1-p...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8W5NUS Patent
LigandPNGBDBM369934((R)-2-Fluoro-N-(3-methyl-1-(3-methyl-2,4-dioxo-1-p...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of C-terminal FLAG-tagged human autotaxin expressed in Freestyle 293 cells assessed as reduction in choline release from LPC 16:0 pre-incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00T0PubMed
LigandPNGBDBM369934((R)-2-Fluoro-N-(3-methyl-1-(3-methyl-2,4-dioxo-1-p...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8W5NUS Patent