null

SMILES CS(=O)(=O)N1CCC(CC1)Nc1ncc2cc(CO)c(=O)n(C3CCCC3)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 370256   

LigandPNGBDBM370256(BDBM467151 | US10233188, Example 143)copy SMILES
Affinity DataKi:  0.190nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9G2VUS Patent
LigandPNGBDBM370256(BDBM467151 | US10233188, Example 143)copy SMILES
Affinity DataKi:  0.190nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM370256(BDBM467151 | US10233188, Example 143)copy SMILES
Affinity DataKi:  0.190nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CSGUS Patent
LigandPNGBDBM370256(BDBM467151 | US10233188, Example 143)copy SMILES
Affinity DataKi:  0.190nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5BVDUS Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM370256(BDBM467151 | US10233188, Example 143)copy SMILES
Affinity DataKi:  2.42nMAssay Description:The purpose of the CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a flu...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5BVDUS Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM370256(BDBM467151 | US10233188, Example 143)copy SMILES
Affinity DataKi:  2.42nMAssay Description:The purpose of the CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a flu...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CSGUS Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM370256(BDBM467151 | US10233188, Example 143)copy SMILES
Affinity DataKi:  2.42nMAssay Description:The mobility shift assay electrophoretically separates the fluorescently labeled peptides (substrate and phosphorylated product) following the kinase...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9G2VUS Patent
LigandPNGBDBM370256(BDBM467151 | US10233188, Example 143)copy SMILES
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM370256(BDBM467151 | US10233188, Example 143)copy SMILES
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails