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SMILES C[C@@]1(O)CCC[C@H]1n1c2nc(NC3CCN(CC3)S(N)(=O)=O)ncc2ccc1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 370296   

LigandPNGBDBM370296(BDBM467191 | US10233188, Example 183)copy SMILES
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant full length wild-type phosphorylated CDK2/Cyclin E1 (unknown origin) expressed in baculovirus expression system assessed as...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0Z4TPubMed
LigandPNGBDBM370296(BDBM467191 | US10233188, Example 183)copy SMILES
Affinity DataKi:  0.100nMAssay Description:The mobility shift assay electrophoretically separates the fluorescently labeled peptides (substrate and phosphorylated product) following the kinase...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9G2VUS Patent
LigandPNGBDBM370296(BDBM467191 | US10233188, Example 183)copy SMILES
Affinity DataKi:  0.100nMAssay Description:The purpose of the CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a flu...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5BVDUS Patent
LigandPNGBDBM370296(BDBM467191 | US10233188, Example 183)copy SMILES
Affinity DataKi:  0.100nMAssay Description:The purpose of the CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a flu...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CSGUS Patent
LigandPNGBDBM370296(BDBM467191 | US10233188, Example 183)copy SMILES
Affinity DataKi:  1.99nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9G2VUS Patent
LigandPNGBDBM370296(BDBM467191 | US10233188, Example 183)copy SMILES
Affinity DataKi:  1.99nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CSGUS Patent
LigandPNGBDBM370296(BDBM467191 | US10233188, Example 183)copy SMILES
Affinity DataKi:  1.99nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5BVDUS Patent
LigandPNGBDBM370296(BDBM467191 | US10233188, Example 183)copy SMILES
Affinity DataKi:  2nMAssay Description:Inhibition of non-phosphorylated CDK6/Cyclin D1 (unknown origin) assessed as reduction in production of ADP using 5-FAM-RRRFRPASPLRGPPK peptide as su...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0Z4TPubMed