null

SMILES Fc1ccc(nc1)-c1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1ncccn1)C(F)(F)F

InChI Key InChIKey=ITMUKFCZWABNED-LJQANCHMSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371768   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371768((R)-4-(2-(5-fluoropyridin-2-yl)-4-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69P5CPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin Ltd.

Curated by ChEMBL
LigandPNGBDBM371768((R)-4-(2-(5-fluoropyridin-2-yl)-4-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4SZXUS Patent