null

SMILES CN1Cc2ccccc2OCCNC(=O)c2cnn3ccc1nc23

InChI Key InChIKey=HQXVNKKSTUDRSP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 374720   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM374720(14-methyl-6,7,13,14-tetrahydro-1,15- ethenopyrazol...)copy SMILEScopy InChI
Affinity DataKd:  0.140nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P12B6US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Turning Point Therapeutics, Inc.

US Patent
LigandPNGBDBM374720(14-methyl-6,7,13,14-tetrahydro-1,15- ethenopyrazol...)copy SMILEScopy InChI
Affinity DataKd:  24nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN0D08US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM374720(14-methyl-6,7,13,14-tetrahydro-1,15- ethenopyrazol...)copy SMILEScopy InChI
Affinity DataKd:  0.140nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN0D08US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Turning Point Therapeutics, Inc.

US Patent
LigandPNGBDBM374720(14-methyl-6,7,13,14-tetrahydro-1,15- ethenopyrazol...)copy SMILEScopy InChI
Affinity DataKd:  24nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P12B6US Patent