null

SMILES Fc1ccc2OCCNC(=O)c3cnn4ccc(NCc2c1)nc34

InChI Key InChIKey=AFTKSWNHMAKIPE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 374721   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM374721(11-fluoro-6,7,13,14-tetrahydro-1,15- ethenopyrazol...)copy SMILEScopy InChI
Affinity DataKd:  0.200nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P12B6US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Turning Point Therapeutics, Inc.

US Patent
LigandPNGBDBM374721(11-fluoro-6,7,13,14-tetrahydro-1,15- ethenopyrazol...)copy SMILEScopy InChI
Affinity DataKd:  0.570nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN0D08US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM374721(11-fluoro-6,7,13,14-tetrahydro-1,15- ethenopyrazol...)copy SMILEScopy InChI
Affinity DataKd:  0.200nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN0D08US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Turning Point Therapeutics, Inc.

US Patent
LigandPNGBDBM374721(11-fluoro-6,7,13,14-tetrahydro-1,15- ethenopyrazol...)copy SMILEScopy InChI
Affinity DataKd:  0.570nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P12B6US Patent