null

SMILES Nc1cc(Cl)c(-c2ccnc(F)c2)c(n1)-c1cccnc1

InChI Key InChIKey=JNYHGOGFLOVUNA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 375229   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375229(3-chloro-5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataKi:  23.9nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375229(3-chloro-5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataKi:  4.80E+3nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375229(3-chloro-5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:The experiment of binding to MT3 sites was carried out on hamster brain membranes using [125I]2-iodomelatonin as radioligand in accordance with the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent