null

SMILES CC#CC(=O)N[C@H]1CCCN(C1)c1c(F)cc(C(N)=O)c2[nH]c3CCC(F)(F)Cc3c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 377401   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Curacyte Chemistry GmbH

LigandPNGBDBM377401(US10266491, Example 73 | US10676434, Example 73 | ...)copy SMILES
Affinity DataIC50: 0.120nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26112M3US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Curacyte Chemistry GmbH

LigandPNGBDBM377401(US10266491, Example 73 | US10676434, Example 73 | ...)copy SMILES
Affinity DataIC50: 0.120nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 ATP (20 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HT2SG3US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Curacyte Chemistry GmbH

LigandPNGBDBM377401(US10266491, Example 73 | US10676434, Example 73 | ...)copy SMILES
Affinity DataIC50: 0.120nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN76Z8US Patent