null

SMILES Cc1ccc(NC(=O)c2ccc(C)c(c2)C(F)(F)F)cc1C#Cc1nn([C@H]2CC[C@H](O)CC2)c2ncnc(N)c12

InChI Key InChIKey=YHVHYWYQEFELOW-HZCBDIJESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 85 hits for monomerid = 378885   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetProto-oncogene tyrosine-protein kinase Src [1-530](Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetEphrin type-B receptor 2(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 165nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 651nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 121nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetLIM domain kinase 1(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 255nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetProtein-tyrosine kinase 2-beta(Mus musculus)
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetSerine/threonine-protein phosphatase(Candida dubliniensis CD36)
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C2065US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))TBA
LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human full length recombinant Src using Cdc2 peptide as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometric sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by automated Qpatch electrophysiological assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human full length recombinant YES using poly(Glu,Tyr)4:1 as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human HCK (230 to 497 residues) using GGMEDIYFEFMGGKKK as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometric ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human full length recombinant LYN using poly(Glu,Tyr)4:1 as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human full length recombinant FYN using Cdc2 peptide as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometric sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human full length recombinant LCK using KVEKIGEGTYGVVYK as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human full length recombinant BLK M287V mutant using poly(Glu,Tyr)4:1 as substrate incubated for 40 mins in presence of [gamma33P-ATP] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant PTK5 (218 to end residues) using GGEEEEYFELVKKKK as substrate incubated for 40 mins in presence of [gamma33P-ATP] by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 121nMAssay Description:Inhibition of human full length recombinant BRK using poly (Glu,Tyr)4:1 as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant ABL (27 to end residues) using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant ABL T315I mutant (27 to end residues) using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma33P-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Kalypsys, Inc.

LigandPNGBDBM378885(US10266537, Compound 93)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant ARG (38 to end residues) using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90DC6PubMed
Displayed 1 to 50 (of 85 total ) | Next | Last >>