null

SMILES [#6]\[#6](=[#6]/c1cc(F)c(-[#8]-c2ccc(cc2)S(=O)(=O)[#7]-[#6]-[#6]-[#8]-[#6]-[#6]-[#8]-[#6]-[#6]-[#8]-[#6]-[#6]-[#7]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#7]-[#6]-[#6]-[#8]-[#6]-[#6]-[#8]-[#6]-[#6]-[#8]-[#6]-[#6]-[#7]S(=O)(=O)c2ccc(-[#8]-c3c(F)cc(\[#6]=[#6](/[#6])-[#6](=O)\[#7]=[#6](\[#7])-[#7])cc3F)cc2)c(F)c1)-[#6](=O)\[#7]=[#6](\[#7])-[#7]

InChI Key InChIKey=MHRFMUXUESQZJZ-CBSZVXRSSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 381674   

TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM381674(US10272079, Compound 31)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381674(US10272079, Compound 31)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent