null

SMILES CN1C(=O)CSc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1

InChI Key InChIKey=NSLGCWMFHWURGT-FPOVZHCZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 385049   

TargetDipeptidyl peptidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM385049((2S)-N-{(1S)-1-Cyano-2-[4-(4-methyl-3-oxo-3,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 12.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76HN2
TargetDipeptidyl peptidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM385049((2S)-N-{(1S)-1-Cyano-2-[4-(4-methyl-3-oxo-3,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 12.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB56W4
TargetDipeptidyl peptidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM385049((2S)-N-{(1S)-1-Cyano-2-[4-(4-methyl-3-oxo-3,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 12.9nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4MTPUS Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM385049((2S)-N-{(1S)-1-Cyano-2-[4-(4-methyl-3-oxo-3,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 12.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6X5T
TargetDipeptidyl peptidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM385049((2S)-N-{(1S)-1-Cyano-2-[4-(4-methyl-3-oxo-3,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 12.9nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q243DZUS Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM385049((2S)-N-{(1S)-1-Cyano-2-[4-(4-methyl-3-oxo-3,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 12.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5CXQ
TargetDipeptidyl peptidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM385049((2S)-N-{(1S)-1-Cyano-2-[4-(4-methyl-3-oxo-3,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 12.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H99949
TargetDipeptidyl peptidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM385049((2S)-N-{(1S)-1-Cyano-2-[4-(4-methyl-3-oxo-3,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 12.9nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KG7US Patent