null

SMILES CCC(CC)Nc1c(Nc2ccc(Cl)c(c2O)S(C)(=O)=NCCN(C)C)c(=O)c1=O

InChI Key InChIKey=TUPIBJFQHPZPII-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 385548   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM385548(US10287278, Example 10 | US10647706, Example 10)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors is determined on a functional test of β-arrest...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2028TWXUS Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM385548(US10287278, Example 10 | US10647706, Example 10)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:To evaluate the direct interaction of the CXCR2 or CXCR1 receptor with β-arrestin 2, a test of β-arrestin 2 recruitment for CXCR2 or CXCR1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1NM8US Patent
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
GALDERMA RESEARCH & DEVELOPMENT

US Patent
LigandPNGBDBM385548(US10287278, Example 10 | US10647706, Example 10)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:To evaluate the direct interaction of the CXCR2 or CXCR1 receptor with β-arrestin 2, a test of β-arrestin 2 recruitment for CXCR2 or CXCR1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1NM8US Patent
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
GALDERMA RESEARCH & DEVELOPMENT

US Patent
LigandPNGBDBM385548(US10287278, Example 10 | US10647706, Example 10)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors is determined on a functional test of β-arrest...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2028TWXUS Patent