null

SMILES CS(=O)(=O)N[C@H]1CCCN[C@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1

InChI Key InChIKey=GWXIWAAZEKCXMJ-RDGPPVDQSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 386065   

TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386065(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  540nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z321Z2US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386065(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  340nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z321Z2US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386065(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  540nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29S1TD1US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))TBA
LigandPNGBDBM386065(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human OX1R expressed in CHO-K1 cells by FLIPR calcium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0ZTSPubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386065(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  540nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ3BCWUS Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386065(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  340nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ3BCWUS Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386065(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human OX2R expressed in CHO-K1 cells by FLIPR calcium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0ZTSPubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386065(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  340nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29S1TD1US Patent