null

SMILES COC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1

InChI Key InChIKey=UXZAJSZFFARTEI-YRPNKDGESA-N

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 386067   

TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50:  2.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50:  2.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50:  2.90nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50:  2.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50:  2.90nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))TBA
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human OX1R expressed in CHO-K1 cells by FLIPR calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0ZTSPubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50:  5.50E+3nMAssay Description:Agonist activity at human OX2R stably expressed in CHO cellsMore data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50:  5.5nMMore data for this Ligand-Target Pair
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))TBA
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3J0TPubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50:  5.5nMMore data for this Ligand-Target Pair
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human OX2R expressed in CHO-K1 cells by FLIPR calcium flux assayMore data for this Ligand-Target Pair
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))TBA
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human OX1R stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66QMSPubMed