null

SMILES Cc1ccc(cc1-c1cnc(NC(=O)c2c(F)cncc2F)cn1)C1=NOC(C)(C)C1=O

InChI Key InChIKey=VWWZLAHHWMLIIM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387272   

TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387272(N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387272(N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q8BUS Patent