null

SMILES CCN(CC)CCNc1nc(\C=C\c2ccc(cc2)S(C)(=O)=O)nc2ccc(Cl)cc12

InChI Key InChIKey=QQMPDLYQWNTWCK-MDWZMJQESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 389616   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Georgia Institute of Technology

LigandPNGBDBM389616(N'-(6-chloro-2-{(E)-2-[4- (methylsulfonyl)phenyl]v...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4T0SUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Georgia Institute of Technology

LigandPNGBDBM389616(N'-(6-chloro-2-{(E)-2-[4- (methylsulfonyl)phenyl]v...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of FLT3 D835Y (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP-FP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27947ZVPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Georgia Institute of Technology

LigandPNGBDBM389616(N'-(6-chloro-2-{(E)-2-[4- (methylsulfonyl)phenyl]v...)copy SMILEScopy InChI
Affinity DataIC50: 6.13E+3nMAssay Description:Inhibition of wildtype FLT3 (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27947ZVPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Georgia Institute of Technology

LigandPNGBDBM389616(N'-(6-chloro-2-{(E)-2-[4- (methylsulfonyl)phenyl]v...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27947ZVPubMed