null
SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2ccc(CCCCn3cc(nn3)C(=O)NCC#N)nn2)c1
InChI Key InChIKey=GBEBRCDTKPPWHA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 405183
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair