null

SMILES CNS(=O)(=O)C[C@H]1CCC(CC1)N(C)c1c(cnn2cccc12)C#N

InChI Key InChIKey=HQQQREPJCCCHMI-AZZIRIGVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 410176   

TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
Elanco Tiergesundheit AG

US Patent
LigandPNGBDBM410176(US10370375, Example 24)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
Elanco Tiergesundheit AG

US Patent
LigandPNGBDBM410176(US10370375, Example 24)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetTyrosine-protein kinase JAK3 [811-1124](Homo sapiens (Human))
Elanco Tiergesundheit AG

US Patent
LigandPNGBDBM410176(US10370375, Example 24)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent