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SMILES CNCc1cc(F)c(c(F)c1)-c1cc2c(n[nH]c2cn1)-c1cnn(C)c1

InChI Key InChIKey=UCUVIFYGOBXXKX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 414705   

LigandPNGBDBM414705(US10435405, Example 122 | US10934288, Example 122)copy SMILEScopy InChI
Affinity DataKi:  5.40nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM414705(US10435405, Example 122 | US10934288, Example 122)copy SMILEScopy InChI
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37ZPXUS Patent
LigandPNGBDBM414705(US10435405, Example 122 | US10934288, Example 122)copy SMILEScopy InChI
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5R98US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM414705(US10435405, Example 122 | US10934288, Example 122)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist potency against carbachol induced inhibition of electrically stimulated guinea pig atria Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM414705(US10435405, Example 122 | US10934288, Example 122)copy SMILEScopy InChI
Affinity DataIC50: 117nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM414705(US10435405, Example 122 | US10934288, Example 122)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM414705(US10435405, Example 122 | US10934288, Example 122)copy SMILEScopy InChI
Affinity DataIC50: 366nMAssay Description:Antagonist potency against carbachol induced inhibition of electrically stimulated guinea pig atria Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))TBA
LigandPNGBDBM414705(US10435405, Example 122 | US10934288, Example 122)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+3nMAssay Description:Antagonist potency against carbachol induced inhibition of electrically stimulated guinea pig atria Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM414705(US10435405, Example 122 | US10934288, Example 122)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist potency against carbachol induced inhibition of electrically stimulated guinea pig atria Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails