null

SMILES ONC(=O)c1ccc(CN2CCCc3cc(Cl)ccc23)c(F)c1

InChI Key InChIKey=YWGJBRYPUNDFFF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 417065   

TargetHistone deacetylase 1(Homo sapiens (Human))
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

US Patent
LigandPNGBDBM417065(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.12E+4nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81GFWUS Patent
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM417065(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of full length recombinant human HDAC6 expressed in baculovirus infected Sf9 insect cells using RHKKAc fluorogenic peptide as substrate pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

US Patent
LigandPNGBDBM417065(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of full length recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using RHKKAc fluorogenic peptide as substrate pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM417065(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 12.4nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81GFWUS Patent