null

SMILES ONC(=O)c1cccc(Nc2nc3cc(Cl)c(Cl)cc3o2)c1

InChI Key InChIKey=OMJQMYFFOQKXJX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 421500   

TargetHistone deacetylase 1(Homo sapiens (Human))
FORMA Therapeutics, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
FORMA Therapeutics, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
FORMA Therapeutics, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
FORMA Therapeutics, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
FORMA Therapeutics, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
FORMA Therapeutics, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
FORMA Therapeutics, Inc.; H. Lee Moffitt Cancer Center and Research Institute, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0HJRUS Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
FORMA Therapeutics, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
FORMA Therapeutics, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
FORMA Therapeutics, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
FORMA Therapeutics, Inc.; H. Lee Moffitt Cancer Center and Research Institute, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
FORMA Therapeutics, Inc.; H. Lee Moffitt Cancer Center and Research Institute, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
FORMA Therapeutics, Inc.

US Patent
LigandPNGBDBM421500(US10508088, Example 1-1 | US10508088, ID HDTK010 |...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280B04US Patent