null

SMILES CC(C)C1(CCc2ccccc2)CC(=O)C(Sc2cc(C)c(NS(=O)(=O)c3ccc(cc3)C(F)(F)F)cc2C(C)(C)C)C(=O)O1

InChI Key InChIKey=BKEQKOQDMKMYFD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 422   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM422(CHEMBL263026 | Dihydropyran-2-one deriv. 27 | N-(5...)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Tested for binding affinity against proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7Z9RPubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM422(CHEMBL263026 | Dihydropyran-2-one deriv. 27 | N-(5...)copy SMILEScopy InChI
Affinity DataKi:  27nM ΔG°:  -10.7kcal/molepH: 6.2 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7Z9RPubMed