null

SMILES CC(C)(O)c1ccc2c(c1)C(=O)N([C@@H](CC(O)=O)c1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1

InChI Key InChIKey=ZJSPHSZNTWLUQB-SUYBVONHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 427061   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM427061(US10544132, Example 14 | US10981898, Example 14 | ...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1N06US Patent
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM427061(US10544132, Example 14 | US10981898, Example 14 | ...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154M5VUS Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM427061(US10544132, Example 14 | US10981898, Example 14 | ...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM427061(US10544132, Example 14 | US10981898, Example 14 | ...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD14WTUS Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM427061(US10544132, Example 14 | US10981898, Example 14 | ...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD14WTUS Patent