null

SMILES Cn1cc(cn1)[C@](C)(O)c1cc2C(=O)N(Cc3ccc(Cl)cc3S(C)(=O)=O)[C@](OCC3(CC3)C(N)=O)(c2c(F)c1)c1ccc(Cl)cc1

InChI Key InChIKey=YLXVSCUQMYZKFT-ZQWAWDFXSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 427127   

TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM427127(1-({[(1R)-2-[(4-chloro-2-methanesulfonylphenyl)met...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154M5VUS Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM427127(1-({[(1R)-2-[(4-chloro-2-methanesulfonylphenyl)met...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1N06US Patent