null

SMILES Clc1cncc(OC(=O)c2ccc3[nH]ccc3c2)c1

InChI Key InChIKey=TYLOEMFGLQBHPE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 429306   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University of Bonn

LigandPNGBDBM429306(acs.jmedchem.1c00409_ST.427 | indole chloropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0JH1PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University of Bonn

LigandPNGBDBM429306(acs.jmedchem.1c00409_ST.427 | indole chloropyridin...)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0JH1PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University of Bonn

LigandPNGBDBM429306(acs.jmedchem.1c00409_ST.427 | indole chloropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9ST6PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM429306(acs.jmedchem.1c00409_ST.427 | indole chloropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 1.93E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1069FPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM429306(acs.jmedchem.1c00409_ST.427 | indole chloropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC13T6PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM429306(acs.jmedchem.1c00409_ST.427 | indole chloropyridin...)copy SMILEScopy InChI
Affinity DataEC50:  4.37E+4nMAssay Description:VeroE6 cells and TMPRSS2-overexpressing VeroE6 (VeroE6TMPRSS2) cells were obtained from the Japanese Collection of Research Bioresource...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC13T6PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University of Bonn

LigandPNGBDBM429306(acs.jmedchem.1c00409_ST.427 | indole chloropyridin...)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9ST6PubMed