null

SMILES Oc1ccc(\C=C(/C#N)C(=O)c2cccs2)cc1O

InChI Key InChIKey=CPXCUSISXFTYFB-UXBLZVDNSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4299   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4299((2E)-3-(3,4-dihydroxyphenyl)-2-(thiophen-2-ylcarbo...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM4299((2E)-3-(3,4-dihydroxyphenyl)-2-(thiophen-2-ylcarbo...)copy SMILEScopy InChI
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibitory activity tested against protein kinase HER-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NKRPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4299((2E)-3-(3,4-dihydroxyphenyl)-2-(thiophen-2-ylcarbo...)copy SMILEScopy InChI
Affinity DataIC50: 3.09E+4nMAssay Description:Inhibitory activity against epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NKRPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM4299((2E)-3-(3,4-dihydroxyphenyl)-2-(thiophen-2-ylcarbo...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086532PubMed