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SMILES C[C@@H](NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N)c1ccccc1

InChI Key InChIKey=UMGQVUWXNOJOSJ-KMHUVPDISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4302   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4302((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phe...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5D7VPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4302((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phe...)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibitory activity against epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NKRPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM4302((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phe...)copy SMILEScopy InChI
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibitory activity tested against protein kinase HER-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58NKRPubMed
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM4302((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phe...)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+4nMAssay Description:Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5F47PCBioAssay