null

SMILES NC(CCC1CC1)(c1ccc(F)c(NC(=O)[C@H]2C[C@@](O)(CN2C(=O)Nc2ccc(Cl)cc2)c2ccccc2)c1)c1ccccn1

InChI Key InChIKey=QSEWLZJVGPKOAW-WELJHWQCSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 433394   

TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM433394(US10562850, Compound 31i | US11066360, Compound 31...)copy SMILEScopy InChI
Affinity DataKi: <50nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates. In these experiments, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FR001PUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM433394(US10562850, Compound 31i | US11066360, Compound 31...)copy SMILEScopy InChI
Affinity DataKi: <50nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6HCGUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM433394(US10562850, Compound 31i | US11066360, Compound 31...)copy SMILEScopy InChI
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails