null

SMILES CS(=O)(=O)N(CC(=O)Nc1cccc(Cl)c1)c1ccccc1Cl

InChI Key InChIKey=UUYQFOSWDVZCAB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 44464   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM44464(2-(2-chloro-N-mesyl-anilino)-N-(3-chlorophenyl)ace...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-methoxyPEPy from rat mGlu5 receptor expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H996BRPubMed
TargetEphrin type-A receptor 4(Mus musculus)
Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM44464(2-(2-chloro-N-mesyl-anilino)-N-(3-chlorophenyl)ace...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4V5TPCBioAssay
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM44464(2-(2-chloro-N-mesyl-anilino)-N-(3-chlorophenyl)ace...)copy SMILEScopy InChI
Affinity DataEC50:  77.6nMAssay Description:Ago-positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells by fluorescence-based calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H996BRPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM44464(2-(2-chloro-N-mesyl-anilino)-N-(3-chlorophenyl)ace...)copy SMILEScopy InChI
Affinity DataEC50:  776nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells by fluorescence-based calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H996BRPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM44464(2-(2-chloro-N-mesyl-anilino)-N-(3-chlorophenyl)ace...)copy SMILEScopy InChI
Affinity DataEC50:  80nMAssay Description:Ago-positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells by fluorescence-based calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H996BRPubMed
TargetEphrin type-A receptor 4(Mus musculus)
Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM44464(2-(2-chloro-N-mesyl-anilino)-N-(3-chlorophenyl)ace...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55KW4PCBioAssay
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM44464(2-(2-chloro-N-mesyl-anilino)-N-(3-chlorophenyl)ace...)copy SMILEScopy InChI
Affinity DataEC50:  780nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells by fluorescence-based calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H996BRPubMed